Synthetic biology offers key advantages in NAD+ production: microbial fermentation or engineered strains optimize metabolic pathways, reducing production costs by over 50% while minimizing chemical pollution. The biosynthesized NAD+ closely mimics the natural structure, enhancing bioactivity for pharmaceutical use. In terms of quality, traditional methods (e.g., chemical synthesis) yield ~98% purity with organic solvent residues (e.g., ethanol ≤300mg/kg). Synthetic biology products achieve ≥99% purity, verified by HPLC and NMR, with stricter controls on heavy metals (lead ≤1mg/kg, arsenic ≤1mg/kg) and microbial limits (total colonies ≤100CFU/g), meeting advanced medical standards and ensuring batch consistency.